Cycloartane Glycosides from Astragalus erinaceus

نویسندگان

  • Tahir Savran
  • Derya Gülcemal
  • Milena Masullo
  • Tamer Karayıldırım
  • Emre Polat
  • Sonia Piacente
  • Özgen Alankuş-Çalışkan
چکیده

One new cycloartane-type saponin, 3-O-[β-D-xylopyranosyl-(1→2)-β-D-xylopyranosyl]-6-O-β-Dglucuronopyranosyl-3β,6α,16β,24(S),25-pentahydroxyxyxloartane (1) was isolated from the MeOH extract of whole plant parts of Astragalus erinaceus along with 5 known saponins (2-6), cyclodissectoside, cycloastragenol, 6-O-β-D-glucopyranosyl-3β,6α,16β,24(S),25-pentahydroxycycloartane, oleifolioside B and 3,6di-O-β-D-xylopyranosyl-3β,6α,16β,24(S),25-pentahydroxycycloartane, respectively. Their structures were established by the extensive use of 1Dand 2D-NMR experiments along with ESIMS and HRMS analysis. The glucuronic acid moiety in cycloartanes is a very unusual finding.

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تاریخ انتشار 2012